I have a wired Xbox360 controller and it won't work.

I set it up too the Xbox 360 preset, still does not work.

The controller is plugged in and shows up on the Xbox360 status.

It used too work now each time I try it doesn't even move the cursor.

Help would be appreciated.

Try this: go to options & controls and click "configure", select custom analog and set the controls manually. It worked for me.

If all else fails, you can manually set a xbox controller to use keys of a Keyboard/ Mouse ( Xpadder Etc.)